Effect of Metals on Kinetic Pathways of Amyloid-β Aggregation
نویسندگان
چکیده
منابع مشابه
Effect of Metals on Kinetic Pathways of Amyloid-β Aggregation
Metal ions, including copper and zinc, have been implicated in the pathogenesis of Alzheimer's disease through a variety of mechanisms including increased amyloid-β affinity and redox effects. Recent reports have demonstrated that the amyloid-β monomer does not necessarily travel through a definitive intermediary en-route to a stable amyloid fibril structure. Rather, amyloid-β misfolding may fo...
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ژورنال
عنوان ژورنال: Biomolecules
سال: 2014
ISSN: 2218-273X
DOI: 10.3390/biom4010101